In around 1740 Leonor married Bernardo Leal, who had also arrived with his family from the Canary Islands. Leonor had three children with Bernardo: Vicente; Juan Antonio; and Joaquin. Bernardo Leal died on March 30, 1748. On February 3, 1750, Leonor married Juan Jose Flores de Abrego y Valdés, originally from Saltillo.
Around 1756, Juan Jose and Leonor established a ranch on the lower Cibolo Creek, “Rancho San Jose de Alamos.” They were granted the first cattle brand in Texas in 1762. Juan and Leonor had seven children: Vicente Delgado; Maria Ignacia Delgado Flores; Juana Francisca Gertrudes Flores; Francisco Remigio Flores; Francisco Luis Flores; Jose Francisco Flores; and Maria Ignacia Flores.
Juan Jose Flores died after January 19, 1779, leaving a will contested by Doña Leonor. In 1779, Doña Leonor Delgado was listed as operating Rancho San Jose de los Alamos. That year the King of Spain approved trade with Louisiana, and the cattle on the ranches outside of San Antonio now could be driven to Opelousas, Louisiana, and sold to the benefit of Louisiana Governor Bernardo de Galvez who was fighting the English forces along the coast.
The life of Doña Leonor Delgado and her extended family illustrates the story of the Canary Islanders who created the city of San Antonio and contributed to the success of the American Revolution by providing cattle to Bernardo de Galvez.